| |
Before rFVIIa
Treatment |
After rFVIIa
Treatment |
P-value |
| Blood loss (ml/kg/hr) |
7.47 ± 1.53 |
|
|
| First 6 hr blood loss (ml/kg/hr) |
- |
2.37 ± 0.67 |
0.001 |
Following 18 hr blood Loss
(ml/kg/hr) |
- |
1.08 ± 0.42 |
0.001 |
| P-RBC (units) |
11.25 ± 3.57 |
5.93 ± 1.70 |
0.001 |
| Platelet (units) |
11.77 ± 4.40 |
3.65 ± 1.42 |
0.001 |
| FFP (units) |
11.35 ± 4.15 |
3.86 ± 1.52 |
0.001 |
| Cryoprecipitate (units) |
10.16 ± 3.76 |
2.91 ± 2.11 |
0.001 |
| PT (seconds) |
11.05 ± 1.29 |
11.32 ± 1.49 |
0.244 |
| INR |
1.21 ± 0.18 |
1.25 ± 0.22 |
0.126 |
| aPTT (seconds) |
45.53 ± 9.81 |
41.25 ± 8.82 |
0.036 |
| ACT(seconds) |
138.19 ±16.15 |
136.60 ± 11.62 |
0.604 |
| Platelet (x103/dl) |
149.74 ± 44.51 |
154.65 ± 50.67 |
0.237 |
| Fibrinogen (gm/l) |
3.59 ± 0.49 |
3.94 ± 0.43 |
0.603 |
| HB (g/dl) |
9.66 ± 2.60 |
10.65 ± 1.73 |
0.211 |
| rFVIIa Intraoperative (6
patients) |
|
|
|
| Postoperative (37
patients) |
|
|
|
| Dose (μg/kg) 93.72 ± 17.39 |
|
|
|
P-RBC=packed- red blood cells, FFP = fresh frozen plazma, HB= heamoglobin,
PT= prothrombin time, INR =international normalized ratio, aPTT =activated prothrombin
time, rFVIIa = activated recombinant factor VII. Values are expressed as
number, %, mean(SD) |
