| Parameter |
Control |
Lidocaine |
Diltiazem |
Esmolol |
p-value |
| SBP (mmHg) |
145.0 ± 2.04 |
136.7 ± 1.29** |
133.1 ± 1.29*** |
131.9 ± 1.39*** |
P<0.0001 |
| DBP (mmHg) |
94.28 ± 0.802 |
91.80 ± 0.88 |
85.15 ± 0.85*** |
82.63 ± 0.83*** |
P<0.0001 |
| HR (per min) |
109.5 ± 1.16 |
101.1 ± 1.31*** |
89.90 ± 1.08*** |
91.40 ± 1.19*** |
P<0.0001 |
| MAP (mmHg) |
111.2 ± 0.88 |
106.8 ± 0.70*** |
101.1 ± 0.80*** |
99.04 ± 0.65*** |
P<0.0001 |
| RPP |
15860 ± 267.3 |
13810 ± 200.5 *** |
11980 ± 205.2 *** |
12060 ± 213.7 *** |
P<0.0001 |
Data are presented as means ± SEM, and p value. ANOVA with repeated measures was used to compare the changes in SBP, DBP, HR, MAP and RPP values. p is
significant at <0.05*, <0.01** and <0.001*** |
