| |
Quartiles of cholesterol absorption marker/total cholesterol (mg/mg*103) |
| |
Q1 |
Q2 |
Q3 |
Q4 |
P-value |
| |
(<4.6) |
(4.6-5.6) |
(5.6-7.2) |
(≥7.3) |
|
| Number of subjects |
30 |
30 |
30 |
31 |
|
| Men (%) |
20 (70.0) |
25 (83.3) |
25 (83.3) |
18 (58.1) |
N.S. |
| Age (years) |
60.4 ± 10.1 |
61.7 ± 11.8 |
61.0 ± 12.1 |
60.6 ± 12.0 |
N.S. |
| Duration of diabetes (years) |
10.9 (7.9) |
12.9 (10.1) |
13.5 (9.2) |
12.8 (9.5) |
N.S. |
| Body Mass Index (kg/m2) |
25.2 ± 4.1 |
25.1 ± 5.7 |
25.6 ± 5.1 |
24.2 ± 4.7 |
N.S. |
| Waist circumference (cm) |
90.7 ± 9.7 |
89.8 ± 10.4 |
89.3 ± 11.8 |
86.5 ± 11.1 |
N.S. |
| Systolic BP (mmHg) |
135.1 ± 11.3 |
133.2 ± 12.5 |
130.3 ± 11.4 |
135.7 ± 13.3 |
N.S. |
| Diastolic BP (mmHg) |
76.7 ± 10.5 |
74.3 ± 11.4 |
74.3 ± 9.2 |
74.8 ± 9.3 |
N.S. |
| Triglycerides (mg/dL) |
157.1 ± 137.6 |
108.1 ± 64.1 |
170.1 ± 256.5 |
109.5 ± 67.7 |
N.S. |
| HDL cholesterol (mg/dL) |
50.4 ± 10.4 |
55.7 ± 16.8 |
54.2 ± 13.6 |
62.4 ± 15.8 |
0.003 |
| LDL cholesterol (mg/dL) |
128.6 ± 31.3 |
131.5 ± 18.1 |
143.4 ± 27.3 |
145.0 ± 25.4 |
0.004 |
| RLP cholesterol (mg/dL) |
6.2 ± 7.0 |
4.5 ± 2.6 |
5.3 ± 2.4 |
5.2 ± 3.2 |
N.S. |
| Cholesterol synthesis marker/total cholesterol (mg/mg*103) |
2.4 ± 1.7 |
2.1 ± 1.4 |
2.0 ± 1.3 |
1.6 ± 0.9 |
0.014 |
| A1C (%) |
7.5 ± 1.2 |
7.4 ± 1.1 |
7.4 ± 1.0 |
7.2 ± 0.9 |
N.S. |
| Fasting blood glucose (mg/dL) |
144.0 ± 32.4 |
147.7 ± 58.0 |
135.5 ± 44.1 |
127.5 ± 32.0 |
N.S. |
| CPR (ng/mL) |
2.0 ± 1.0 |
1.8 ± 1.1 |
1.7 ± 1.1 |
1.3 ± 0.8 |
0.009 |
| hs-CRP (ng/mL) |
1098.2 ± 1560.4 |
1506.4 ± 1936.4 |
971.8 ± 1140.0 |
877.4 ± 1799.3 |
N.S. |
| History of coronary artery disease (%) |
1 (3.3) |
2 (6.7) |
1 (3.3) |
1 (3.3) |
N.S. |
| History of stroke (%) |
4 (13.3) |
0 (0.0) |
2 (6.7) |
3 (10.0) |
N.S. |
| Hypertension (%) |
12 (40.0) |
10 (33.3) |
8 (26.7) |
12 (38.7) |
N.S. |
| Smoking (%) |
7 (23.3) |
4 (13.3) |
4 (13.3) |
8 (25.8) |
N.S. |
CPR: C-peptide reactivity. CPR (reference value): 1.2 to 2.0 ng/mL, hs-CRP: high-sensitivity C-reactive protein