Subsets of subjects |
% glucoses
<3.3 mmol/L |
%glucoses <2.75 mmol/L |
%glucoses
< 2.2 mmol/L |
HbA1c |
All subjects (n=153) |
6.5 ± 5.7 |
2.5 ± 3.5 |
0.5 ± 1.4 |
8.7 ± 1.4 |
Low CPT-1 subset (n=30) |
6.4 ± 3.9 |
2.2 ± 1.0 |
0.4 ± 0.1 |
8.0 ± 0.8 * |
Normal CPT-1 subset (n=123) |
6.5 ± 6.0 |
2.6 ± 3.8 |
0.5 ± 1.4 |
8.8 ± 1.4 |
ACDAM mutations (n=2) |
4.00 ± 2.8 |
0.0 |
0.0 |
9.2 ± 0.7 |
Free carnitine greater than 2 SD below mean (n=3) |
4.7 ± 1.2 |
1.7 ± 1.2 |
0.0 |
8.3 ± 2.5 |
Free carnitine less than 10 µmol/L (n=1) |
6.2 |
3.0 |
0.0 |
6.3 |
* significantly lower than those with normal CPT-1 levels; p= 0.0003; 95% CI ( -1.22, -0.27) |