Figure 5: The role of LB extract and taurine in high glucose-induced breakdown of the epitheleal barrier in ARPE-19 monolayer. (a) The effect of LB extract and taurine on integrity of tight junctions between ARPE-19 cells was determined by transepithelial resistance (TER) values. The vertical axis represents the TER expressed in Ohm·cm2. (b) The effect of LB extract and taurine on 70 kDa FITCdextran permeability in high glucose-treated ARPE-19 cells was determined. The vertical axis represents the fluorescent intensity. Values are means ± SEM. (n =5 independent experiments). #P<0.01 versus Control, *P<0.05, **P<0.01 versus high glucose (HG). AU, arbitrary units.