| Metabolic |
TCF7L2-rs290487 |
P
Value* |
13q31.1-rs1359790 |
P
Value* |
CDKAL1-rs9465871 |
P
Value* |
| factors† |
TT |
CT |
CC |
AA |
AG |
GG |
TT |
CT |
CC |
| Men, N |
122 |
134 |
31 |
|
26 |
114 |
141 |
|
58 |
145 |
86 |
|
| FPG, mmol/L |
5.4(1.2) |
5.3(1.2) |
5.3(1.1) |
0.800 |
5.3(1.2) |
5.3(1.1) |
5.4(1.2) |
0.583 |
5.1(1.1) |
5.4(1.2) |
5.5(1.2) |
0.072 |
| HbA1c, % |
5.9(1.1) |
5.9(1.1) |
5.8(1.1) |
0.757 |
5.9(1.1) |
5.9(1.1) |
5.9(1.1) |
0.887 |
5.8(1.1) |
5.9(1.1) |
5.9(1.1) |
0.384 |
| TC, mmol/L |
4.2(1.2) |
4.3(1.2) |
4.3(1.2) |
0.461 |
4.3(1.2) |
4.3(1.2) |
4.2(1.2) |
0.497 |
4.1(1.2) |
4.3(1.2) |
4.3(1.2) |
0.222 |
| TG, mmol/L |
1.3(1.8) |
1.4(1.7) |
1.1(1.8) |
0.209 |
1.2(1.6) |
1.3(1.8) |
1.3(1.8) |
0.933 |
1.3(1.8) |
1.3(1.8) |
1.4(1.7) |
0.672 |
| LDLC, mmol/L |
2.6(1.3) |
2.7(1.3) |
2.7(1.3) |
0.543 |
2.6(1.3) |
2.7(1.3) |
2.6(1.3) |
0.502 |
2.5(1.4) |
2.7(1.3) |
2.6(1.3) |
0.135 |
| HDLC, mmol/L |
1.1(1.3) |
1.1(1.3) |
1.1(1.2) |
0.952 |
1.2(1.3) |
1.1(1.2) |
1.1(1.3) |
0.101 |
1.1(1.3) |
1.1(1.3) |
1.1(1.3) |
0.979 |
| BMI |
25.2(1.1) |
24.8(1.1) |
24.5(1.1) |
0.504 |
25.9(1.1) |
24.7(1.1) |
25.0(1.1) |
0.224 |
24.9(1.2) |
24.9(1.1) |
25.0(1.1) |
0.983 |
| WHR |
0.88(1.1) |
0.88(1.1) |
0.88(1.1) |
0.936 |
0.90(1.1) |
0.88(1.1) |
0.88(1.1) |
0.353 |
0.88(1.1) |
0.88(1.1) |
0.88(1.1) |
0.873 |
| Women, N |
245 |
283 |
81 |
|
41 |
244 |
321 |
|
140 |
298 |
179 |
|
| FPG, mmol/L |
5.2(1.2) |
5.3(1.2) |
5.3(1.2) |
0.806 |
5.3(1.1) |
5.3(1.2) |
5.2(1.2) |
0.846 |
5.2(1.1) |
5.3(1.2) |
5.3(1.2) |
0.261 |
| HbA1c, % |
5.9(1.1) |
6.0(1.1) |
6.0(1.1) |
0.545 |
6.0(1.1) |
6.0(1.1) |
6.0(1.1) |
0.872 |
5.9(1.1) |
6.0(1.1) |
6.1(1.1) |
0.025 |
| TC, mmol/L |
4.6(1.2) |
4.5(1.2) |
4.5(1.2) |
0.765 |
4.5(1.3) |
4.6(1.2) |
4.5(1.2) |
0.757 |
4.7(1.2) |
4.5(1.2) |
4.5(1.2) |
0.034 |
| TG, mmol/L |
1.2(1.7) |
1.2(1.7) |
1.3(1.6) |
0.578 |
1.2(1.6) |
1.3(1.7) |
1.2(1.6) |
0.575 |
1.3(1.7) |
1.2(1.7) |
1.2(1.7) |
0.108 |
| LDLC, mmol/L |
2.8(1.3) |
2.8(1.3) |
2.8(1.4) |
0.914 |
2.8(1.4) |
2.8(1.3) |
2.8(1.3) |
0.894 |
2.9(1.3) |
2.8(1.3) |
2.8(1.3) |
0.121 |
| HDLC, |
1.3(1.3) |
1.3(1.3) |
1.3(1.3) |
0.391 |
1.3(1.2) |
1.3(1.3) |
1.3(1.3) |
0.784 |
1.3(1.3) |
1.3(1.3) |
1.3(1.3) |
0.712 |
| BMI |
24.4(1.1) |
25.0(1.1) |
25.0(1.1) |
0.106 |
25.4(1.1) |
24.8(1.1) |
24.8(1.1) |
0.374 |
25.2(1.1) |
24.7(1.1) |
24.6(1.1) |
0.293 |
| WHR |
0.84(1.1) |
0.84(1.1) |
0.83(1.1) |
0.525 |
0.85(1.1) |
0.84(1.1) |
0.83(1.1) |
0.219 |
0.83(1.1) |
0.84(1.1) |
0.84(1.1) |
0.491 |
† Continuous variables were expressed as Mean (S.D.)
* Generalized linear model adjusted age. |
