Table 5

	Concentration (µg equivalents/g tissue)				Tissue-to-Blood Ratio
Tissue	0.25 hr a	1 hr	4 hr	24 hr	0.5 hr	4 hr	8 hr	24 hr
Blood	2.92	3.56	1.02	0.15	1.00	1.00	1.00	1.00
Brain	0.24	0.53	0.14	BLQ b	0.08	0.15	0.14	NC
Harderian Gland	1.25	3.73	1.24	0.31	0.43	1.05	1.21	2.10
Heart	2.64	2.58	0.72	0.09	0.90	0.76	0.70	0.64
Kidney	11.0	14.1	3.96	0.41	3.75	3.97	3.87	2.79
Liver	32.8	16.3	9.06	1.72	11.2	4.57	8.87	11.7
Muscle	0.75	1.65	0.47	BLQ	0.26	0.46	0.46	NC

^an = 1 animal per time point
^bAbbreviations: BLQ: Below Limit of Quantification; NC = Not Calculated

Table 5: Tissue Concentrations and Tissue-to-Blood Ratios of Radioactivity in Male Rats After A Single Oral Administration of 25 mg/kg [¹⁴C]-Remogliflozin etabonate.