Organ
Treatment
Group I
(untreated control)
Group II
(STZ)
Group III
(C
60
HyFn control)
Group IV
(C
60
HyFn prophylactic regime + STZ)
Group V
(STZ + C
60
HyFn therapeutic regime)
TBARS content, nM/mg protein
Liver
45 ± 5.2
173 ± 23.0
*
28 ± 6.3
39 ± 9.1
#
32 ± 7.2
#
Brain
27 ± 7.4
59 ± 9.5
*
31 ± 4.8
47 ± 8.2
25 ± 6.8
#
Carbonylated protein content, nM/mg protein
Liver
4 ± 0.6
24 ± 1.7
*
3 ± 0.3
5 ± 0.7
#
2 ± 0.5
#
Brain
8 ± 0.4
18 ± 0.6
*
11 ± 0.4
19 ± 0.8
*
7 ± 0.9
#
*
P < 0.05 vs. intact control (Group I)
#
P < 0.05 vs. STZ-diabetes (Group II)
Table 2:
Levels of oxidative stress indices (LPO levels, carbonylated protein content) in brain tissues of control and experimental rats (n=7).
