| Variable (Diabetic Range) |
Thiamine Treatment |
Placebo |
| |
Baseline |
Therapy |
Washout |
Baseline |
Therapy |
Washout |
| Creatine Kinase U/L(M:38-174; F:96-140) |
81.85±52.30 |
86.20±62.04g |
141.90±114.20id |
69.95 ± 55.35 |
58.30 ± 37.19g |
75.85±42.78 |
| Uric acid mg/dl(3.5-8.5) |
4.65±10.05 |
3.75±1.49h |
4.82±1.47e |
3.99±1.09 |
40.03±1.70 |
4.45±0.93 |
| Blood Urea Nitrogen mg/dl (7-21) |
11.70 ± 4.87 |
12.45 ± 5.24 |
140.05 ±4.76d |
12.25±2.24 |
9.9 ±4.59d,g |
14.8 ±5.92d |
| GFR (ml/min) (<60 chronic renal disease) |
85 ±19 |
90±30 |
77 ±20 |
93 ± 23 |
97± 18 |
87± 21
P’<0.05,
P”<0.01 |
| Serum creatinine mg/dl) (0.8-1.4) |
0.915±0.195 |
0.84±0.28g |
0.95±0.25 |
0.84±0.24 |
0.77 ± 0.20i |
0.94±0.21 |
| Urine creatinine (mg/dl) (30-125) |
42.4±25.63 |
45.86±31.14 |
43.73±37.37 |
42.65±31.76 |
59.1±41.37d |
66.59±34.78e |
| Diastolic BP (mmHg)(<90) |
87 ± 7 |
85 ± 9 |
87 ± 7 |
84 ± 6 |
84 ± 8 |
83 ± 7 |
| Systolic BP (mmHg)(<140) |
126 ± 14 |
133 ± 20 |
135 ± 14
P’<0.05 |
131 ± 10 |
130 ± 17 |
130 ± 13 |
