| Sample treatment |
Sample size
(n) |
SvPVM
Mean (SE) |
SvM
Mean (SE) |
SvER
Mean (SE) |
Percentage
PVM-mitochondrial association |
Percentage
PVM-ER association |
Untreated,
4 hrs |
31 |
3.20 (0.16) |
0.58 (0.07) |
1.78 (0.22) |
18 |
56 |
Nocodazole,
4 hrs |
31 |
3.70 (0.17) |
0.33 (0.08) |
1.79 (0.15) |
9 |
47 |
Untreated,
20 hrs |
30 |
2.70 (0.19) |
0.61 (0.06) |
0.80 (0.13) |
23 |
30 |
Nocodazole,
20 hrs |
30 |
3.22 (0.19) |
0.81 (0.09) |
1.21 (0.20) |
25 |
38 |
Pyrimethamine
20 hrs |
30 |
2.96 (0.14) |
0.79 (0.09) |
1.00 (0.14) |
27 |
34 |
ER: Endoplasmic Reticulum. PVM: Parasitophorous Vacuole Membrane. The extent of PVM-organelle association was measured at 4 hrs and 20 hrs post-infection.
The specific parameters measured are the Surface to Volume ratios (Sv) of the PVM (SvPVM), PVM-associated mitochondria (SvM) and PVM-associated Endoplasmic
Reticulum (SvER), all relative to the volume of the PV. The mean surface densities and the Standard Error (SE) for the sample size measured are presented. The extent of PVM-mitochondrial and PVM-ER association was represented as a percentage of their surface densities (SvM and SvER) relative to SvPVM. The values for the mean surface densities and the percentage association were rounded off to the level of significance indicated |
