| SNP (major/minor allele) |
Cases (%) |
Controls (%) |
Pc-value |
OR |
95%CI |
| -1722(T>C)
(rs733618) |
669 (84) |
123 (16) |
710 (90) |
82 (10) |
0.0294* |
1.6 |
1.2-2.1 |
| -1661 (A>G)
(rs4553808) |
503 (64) |
289 (36) |
574 (72) |
218 (28) |
0.0182* |
1.5 |
1.2-1.9 |
| -651 (C>T)
(rs11571318) |
714 (90) |
78 (10) |
736 (93) |
56 (7) |
0.658 |
1.4 |
1.0-2.1 |
| -318 (C>T)
(rs5742909) |
717 (91) |
75 (9) |
743 (94) |
49 (6) |
0.21 |
1.6 |
1.1-2.3 |
| +49 (A>G)
(rs231775) |
498 (63) |
294 (37) |
576 (73) |
216 (27) |
3.724E-04* |
1.6 |
1.3-1.9 |
| -819 (C>T)
(rs231726) |
540 (68) |
252 (32) |
592 (75) |
200 (25) |
0.0532 |
1.4 |
1.1-1.7 |
| CT60
(+6230G>A)
(rs3087243) |
347 (44) |
445 (56) |
409 (52) |
383 (48) |
0.0252* |
1.4 |
1.1-1.7 |
The table shows counts and percentages between brackets of the alleles of seven CTLA-4 SNPs studied. P-value (Pc) is corrected for multiple testing of seven SNPs. Odds
Ratio (OR) and corresponding 95% confidence intervals are given for the minor allele |
