SNP (genotype) |
Cases (%) |
Controls (%) |
P-value |
-1722 (TT/TC/CC) |
282 (71) |
105 (27) |
9 (0.03) |
318 (0.80) |
74 (19) |
4 (1) |
0.084 |
-1661 (AA/AG/GG) |
159 (40) |
185 (47) |
52 (13) |
208 (53) |
158 (40) |
30 (7) |
0.0098* |
-651 (CC/CT/TT) |
318 (80) |
78 (20) |
0 (0) |
343 (86) |
50 (13) |
3 (1) |
0.112 |
-318 (CC/CT/TT) |
325 (82) |
67 (17) |
4 (1) |
347 (88) |
49 (12) |
0 (0) |
0.84 |
49 (AA/AG/GG) |
157 (40) |
184 (46) |
55 (0.14) |
211 (53) |
154 (39) |
31 (8) |
0.0028* |
-819 (CC/CT/TT) |
181 (46) |
178 (45) |
37 (9) |
214 (54) |
164 (41) |
18 (5) |
0.098 |
+6230 (AA/AG/GG) |
76 (19) |
195 (49) |
125 (32) |
107 (27) |
195 (49) |
94 (24) |
0.112 |
The table shows counts and percentages between brackets of the genotypes of seven CTLA-4 SNPs studied.
P-values are corrected for multiple testing of seven SNPs |