VARIABLES |
BASELINE |
END OF 4TH
WEEK |
END OF 8TH WEEK |
END OF 12TH
WEEK |
F value |
p value |
CARDIOVASCULAR |
|
|
|
|
|
|
RASBP (mmHg) |
136.20±16.81 |
135.00±14.40 |
125.30±13.06*b |
123.90±13.00*b |
3.94 |
0.01* |
RADBP (mmHg) |
82.75±8.33 |
80.75±5.84 |
75.20±5.47*b |
71.55±5.84*b |
12.54 |
0.00* |
RRPP (beat/min/mmHg) |
11307.75±2002.74 |
10492.35±1540.40 |
9791.05±1570.99*b |
8979.90±1816.44*b |
6.49 |
0.00* |
PULMONARY |
|
|
|
|
|
|
VO2max (kg/ml/min) |
21.55±2.44 |
22.01±3.62 |
27.35±3.76*b |
28.02±4.17*b |
18.57 |
0.00* |
FVC (litres) |
1.54±0.39 |
1.55±0.39 |
1.72±0.45 |
1.86±0.52 |
2.46 |
0.07 |
FEV1(litres) |
1.36±0.41 |
1.46±0.43 |
1.68±0.33*b |
1.77±0.39*b |
4.71 |
0.00* |
BIOCHEMICAL |
|
|
|
|
|
|
HbA1C (%) |
6.97±0.90 |
|
|
6.02±0.74*b |
t=13.32 |
0.00* |
Key: RASBP= Resting arterial systolic BP, RADBP= Resting arterial diastolic BP, RRPP= Resting rate pressure product, VO2max= oxygen uptake, FVC= Forced vital
capacity, FEV1= Forced expiratory volume in one second, HbA1c = Glycosylated haemoglobin, *b = significantly different from baseline at p<0.05, *= significant difference
across the week |