Parameter |
Obese
non-diabetic patients |
Obese diabetic patients |
Non obese diabetic patients |
Controls |
P-value |
P1 |
P2 |
P3 |
P4 |
Age (yr, mean ± SD) |
37.24±8.12 |
38.46±10.90 |
39±5 |
35.32±7.31 |
>0.05 |
>0.05 |
>0.05 |
>0.05 |
>0.05 |
Body mass index (kg/m2) |
32.17±2.50 |
35.98±2.14 |
21±2 |
22.49±1.21 |
<0.05* |
<0.05* |
<0.01* |
<0.01* |
>0.05 |
Gender
Male (n, %)
Female (n, %) |
8(40)
12(60) |
7(35)
13(65) |
9(45)
11(55) |
7(50)
7(50) |
>0.05 |
|
|
|
|
Triglyceride
(mmol/L) |
4.50±0.18 |
4.91±0.40 |
1.64±0.12 |
1.51±0.28 |
<0.01* |
<0.001* |
<0.001* |
<0.001* |
>0.05 |
Total cholesterol
(mmol/L) |
8.69±0.53 |
9.33±0.38 |
5.59±0.59 |
4.93±0.78 |
<0.01* |
<0.01* |
<0.001* |
<0.001* |
>0.05 |
HDL- cholesterol
(mmol/L) |
1.04±0.24 |
0.78±0.21 |
1.31±0.15 |
1.43±0.23 |
>0.05 |
>0.05 |
<0.001* |
<0.001* |
>0.05 |
LDL- cholesterol
(mmol/L) |
3.48±0.34 |
3.59±0.29 |
3.24±0.28 |
3.07±0.40 |
>0.05 |
>0.05 |
<0.01* |
<0.05* |
>0.05 |
Fasting Glucose (mmol/L) |
6.67±0.29 |
12.78±1.67 |
12.60±0.56 |
5.29±0.23 |
<0.01** |
<0.001** |
<0.001** |
<0.001** |
<0.001** |
Serum Insulin (µIU/ml) |
15.87±1.0 |
17.80±1.89 |
16.01±1.10 |
10.56±0.80 |
<0.05* |
<0.05* |
<0.001** |
<0.001** |
<0.01** |
HOMAIR |
4.71±0.51 |
10.19±1.90 |
8.98±0.96 |
2.49±0.60 |
<0.05* |
<0.001** |
<0.01** |
<0.001** |
<0.001** |
Serum visfatin (ng/ml) |
34.61±4.68 |
42.55±7.16 |
23.5±5 |
17.4±3.44 |
<0.05* |
<0.01** |
<0.001** |
<0.001** |
>0.05 |
*significant (p< 0.05); ** highly significant (p< 0.01); HDL: High Density Lipoproteins; LDL: Low Density Lipoproteins; P1: Comparison between obese non diabetic & obese diabetic patients; P2: Comparison between obese non diabetics & control subjects; P3: Comparison between obese diabetics & control subjects ; P4: Comparison between non obese diabetics & control subject |