Study reference |
Number of studies |
Population |
Total subjects |
Indices examined |
Outcomes |
Analysis type |
Ashwell et al. (2012) |
31 |
4 Europe
2 South America
2 Australasia
6 Asia
2 Middle-East
1 Caribbean
14 other |
123,231 men
182,620 women |
BMI, WC, WHtR |
Incident and prevalent T2DM, Hypertension, Dyslipidaemia, MetS, CVD |
Pooled ROC analysis |
Carmienke et al. (2013) |
18 |
6 Europe
10 North America
2 Australasia |
693,739
men and women |
BMI, WC, WHR |
All-cause mortality |
Pooled RR using categorical variables |
Coutinho et al. (2011) |
5 |
2 Europe
2 North America
1 Asia |
15,923
(59% men) |
BMI, Central obesity defined as WC or WHR |
CAD mortality |
Individual participant meta-analysis
HR by obesity tertiles |
Czernichow et al. (2011) |
9 |
Europe |
82,864
(54-62% women) |
BMI, WC, WHR |
All-cause and CVD mortality |
Individual participant meta-analysis
HR comparing upper quintiles to lower quintiles and for a 1 SD increase in each index
ROC and relative integrated discrimination improvement statistics (RIDI) |
de Koning et al. (2007) |
15 |
Not stated |
258,114 (35.7% men) |
WC, WHR |
Incident CVD events |
Pooled RR comparing highest to lowest quantiles of WC and WHR |
Huxley et al. (2008) |
21 |
Asian (73%)
Caucasian (27%) |
>263,000
men and women |
BMI, WC, WHR |
Prevalent T2DM, Hypertension |
Individual participant meta-analysis
OR stratified by ethnicity |
Kodama et al. (2012) |
15 |
8 Western
7 Non-Western |
120,012
(men 21-78%) |
BMI, WC, WHR, WHtR |
Incident T2DM |
Pooled RR for 1 SD increase in each index |
Lee et al. (2008) |
10 |
1 Europe
7 Asian
1 Caribbean
1 Iran |
88,514
(54% women) |
BMI, WC, WHR, WHtR |
Incident and prevalent T2DM, Hypertension, Dyslipidaemia |
Pooled ROC analysis |
Mohan (2008) |
19 |
Asian
(62.8%)
Caucasian (36.7%)
Pacific Islanders
(0.5%) |
>173,709
(53% women) |
BMI, WC, WHR, WHtR |
Prevalent Hypertension |
Individual participant meta-analysis
Adjusted linear regression between indices and SBP/DBP stratified by ethnicity
OR for hypertension stratified by ethnicity
ROC analysis stratified by ethnicity and overall pooled results |
Nyamdorj et al. (2008) |
16 |
Asia |
9,095 men
11,732 women |
BMI, WC, WHR, WHtR |
Prevalent T2DM, Hypertension |
Individual participant meta-analysis
OR for 1 SD increase in each index
ROC analysis |
van Dijk et al. (2012) |
20 |
11 Europe
7 North America
1 Turkey
1 Australasia |
21,139 men
24,139 women |
BMI, WC, WHR, WHtR |
Prevalent FPG, SBP, DBP, HDL-C, LDL-C, Total-C, TAG |
Pooled mean Pearson correlation coefficients between each index and cardiometabolic features |
Vazquez et al. (2007) |
32 |
9 Europe
12 North America
4 Asia
7 Other |
72-31,702
men and women |
BMI, WC, WHR |
Incident T2DM |
Pooled RR for a 1 SD increase in each index |
|