Figure 4: Increased GFAP and fibronectin expression in retinas from Akita/+; TSP1 -/- mice. GFAP and fibronectin staining of the retinal sections from 7 month wild-type, Akita/+ and Akita/+; TSP1-/- male mice are shown (scale bar= 50 μM). Please note the increase in GFAP and fibronectin expression in Akita/+; TSP1-/- male mice compared to wild-type or Akita/+ male mice. Experiments were repeated with eyes from 5 mice with similar results.