Study Country Ethnicity Sample size Genotype frequency in cases Genotype frequency in controls P HWE Cases Controls CC AC AA CC AC AA Yang,2003 [5] UK European 64 66 12 31 21 13 38 15 Yes Awata,2005 [6] Japan East Asian 175 203 95 70 10 93 91 19 Yes Buraczynska,2007 [7] Poland European 195 91 29 80 86 29 43 19 Yes Abhary,2009 [8] Australia European 75 93 17 35 23 26 43 24 Yes Abhary,2009 [8] Australia European 136 181 31 74 31 45 91 45 Yes Nakamura,2009 [9] Japan East Asian 177 292 85 70 22 163 107 22 Yes Chun,2010 [10] Korea East Asian 253 134 123 115 15 92 36 6 Yes Yang,2011 [11] China East Asian 129 138 66 47 16 82 51 5 Yes

Table 1: Characteristic of the studies included in the meta-analysis between rs699947 polymorphism in the VEGFA gene and diabetic retinopathy.