Parameters   C I+SAL I+VEGF DI+SAL DI+VEGF   Morphometric                 LV mass (g/kg) Initial 1.02±0.02 1.06±0.01 1.05±0.04 1.04±0.01 1.05±0.05   Final 1.06±0.03 1.15±0.02# 1.09±0.01 1.14±0.03# 1.09±0.04     LVEDD (cm) Initial 0.65±0.01 0.75±0.01* 0.76±0.02* 0.77±0.03* 0.76±0.01*   Final 0.67±0.03 0.98±0.02#* 0.79±0.02*† 0.88±0.03#*† 0.74±0.02 Systolic                 EF (%) Initial 74±2 48±3* 47±2* 51±3* 52±3*   Final 71±1 31±2#* 53±3*† 44±3*† 53±2*‡     VCF (circ/s) (10-4) Initial 56±3 38±2* 37±3* 38±3* 39±1*   Final 53±4 30±3#* 39±3* 29±2#* 38±3* Diastolic                 IVRT (ms) Initial 1.81±0.07 1.81±0.09 1.79±0.08 1.94±0.08 1.90±0.09   Final 1.77±0.05 2.00±0.07* 1.95±0.05* 2.10±0.03* 1.93±0.05*     EDT (ms) Initial 1.87±0.11 1.97±0.10 1.99±0.12 1.83±0.09 1.81±0.07   Final 1.81±0.15 2.05±0.15 2.02±0.10 2.10±0.07# 2.01±0.04# Global Function                 MPI Initial 0.39±0.01 0.46±0.03 0.45±0.01 0.44±0.03 0.45±0.01   Final 0.43±0.02 0.55±0.02#* 0.47±0.02† 0.48±0.01† 0.42±0.02 Values are expressed as mean ± SEM. LV mass – Left ventricular mass corrected by body weight; LVEDD – Left ventricular end-diameter during diastole; EF - Ejection fraction; VCF - Velocity of circumferential fiber shortening; EDT– Peak E deceleration time; IVRT– Left ventricular isovolumetric relaxation time; MPI - Myocardial performance index. # p<0.05 vs. initial evaluation; * p<0.05 vs. C; † p<0.05 vs. I+SAL; ‡ p<0.05 vs. DI+SAL (n=8 for each group)

Table 2: Initial and final echocardiographic measurements in control (C), myocardial infarction + saline (I+SAL), myocardial infarction + VEGF (I+VEGF), diabetes + myocardial infarction + saline (DI+SAL), and diabetes + myocardial infarction + VEGF (DI+VEGF) groups.