†indicates a significant difference from the corresponding value in GK rats

Figure 4: Comparison of the renal histopathology in Goto-Kakizaki (GK)rats and the modified GK substrain susceptible to diabetic nephropathy (T2DN) at 18 months of age: glomerular injury scores (PanelA), renal fibrosis (PanelB) and the formation of protein casts as an indicator of tubular necrosis (C) Numbers in parentheses indicate the number of rats studied per group. Values are means ± S.E.