New Test

Subjects with the disease

Subjects without the  disease

  Total

       Positive

           a (TP)

        b ( FP)

   a +b (TP + FP)

      Negative

           c (FN)

        d (TN)

   c +d(FN + TN)

Total

         a +c (TP + FN)

     b +d( FP + TN)

a+ b+ c+ d (TP+TN+FP+FN)

Table 2: Assessment of new diagnostic test accuracy in relation to the gold standard