Average dose

 Average dose for control (mg/day)

 

 for case

 0

 0.1-0.299

 0.3-0.625

 0.626+

 Total

(mg/day)

 (1)

(2)

(3)

(4)

 

 0    (1)

 6

2

3

1

12

 

(6.00)

(3.33)

(2.04)

(1.23)

 

0.1-0.299 (2)

9

4

2

1

16

 

(8.27)

(4.00)

(1.48)

(0.73)

 

0.3-0.625 (3)

9

2

3

1

15

 

(9.66)

(2.17)

(3.00)

(1.32)

 

0.626+ (4)

12

1

2

1

16

 

(11.80)

(1.07)

(1.90)

(1.00)

 

 Total

36

9

10

4

59
Table 1: Average doses of conjugated oestrogen used by cases and matched control: Los Angeles endometrial cancer study [1] (The parenthesized values are maximum likelihood estimates of expected frequencies under the CLDPS(3) model).