| |
Statistical methods |
| Expos. Ratio |
ni |
σ2 |
IP/FCP/CP/RCP |
GEE |
| Constant 3:3 |
6 |
0 |
0.032 |
0.048 |
| |
|
0.5 |
0.042 |
0.060 |
| |
|
1.0 |
0.048 |
0.066 |
| |
|
2.0 |
0.052 |
0.092 |
| |
6-42 |
0 |
0.038 |
0.062 |
| |
|
0.5 |
0.068 |
0.082 |
| |
|
1.0 |
0.050 |
0.090 |
| |
|
2.0 |
0.028 |
0.090 |
| Constant 1:5 |
6 |
0 |
0.032 |
0.052 |
| |
|
0.5 |
0.048 |
0.052 |
| |
|
1.0 |
0.040 |
0.066 |
| |
|
2.0 |
0.040 |
0.094 |
| |
6-42 |
0 |
0.050 |
0.074 |
| |
|
0.5 |
0.058 |
0.068 |
| |
|
1.0 |
0.038 |
0.068 |
| |
|
2.0 |
0.048 |
0.110 |
| |
|
|
IP |
FCP/CP |
RCP |
GEE |
RCP_bw |
| Varying |
6 |
0 |
0.046 |
0.046 |
0.034 |
0.060 |
0.040 |
| |
|
0.5 |
0.168 |
0.056 |
0.052 |
0.096 |
0.044 |
| |
|
1.0 |
0.284 |
0.058 |
0.050 |
0.088 |
0.040 |
| |
|
2.0 |
0.506 |
0.050 |
0.042 |
0.104 |
0.044 |
| |
6-42 |
0 |
0.046 |
0.044 |
0.034 |
0.060 |
0.038 |
| |
|
0.5 |
0.502 |
0.054 |
0.054 |
0.094 |
0.046 |
| |
|
1.0 |
0.676 |
0.036 |
0.030 |
0.092 |
0.024 |
| |
|
2.0 |
0.788 |
0.054 |
0.044 |
0.104 |
0.044 |
Expos. ratio=ratio of number of exposed to control subjects in a cluster; Varying ratio means the exposure ratios vary randomly from cluster to cluster; ni=number of subjects in each cluster; σ2=between cluster variance; IP=Independent Poisson model; FCP=Fixed Cluster Poisson model; CP=Conditional likelihood Poisson estimation; GEE=Generalized Estimating Equations with empirical standard error; RCP=Random Cluster effects Poisson model; RCP_bw=Random Cluster effects Poisson model where the within- and between- cluster effects were separated. |
