|
n |
R |
(α=0.05) |
(α=0.01) |
| β |
M |
N |
β |
M |
N |
|
10 |
5 |
47.94 (1.06) |
34.95 (0.88) |
68.05 (0.92) |
45.12 (1.76) |
23.23 (1.36) |
62.06 (1.55) |
| 10 |
53.40 (0.93) |
35.48 (0.78) |
72.50 (0.79) |
49.78 (1.43) |
23.59 (1.02) |
63.03 (1.19) |
| 15 |
56.29 (0.80) |
35.81 (0.68) |
76.31 (0.66) |
50.66 (1.33) |
23.55 (0.88) |
65.68 (1.00) |
| 20 |
58.54 (0.73) |
35.26 (0.62) |
76.91 (0.59) |
51.64 (1.11) |
22.96 (0.79) |
64.49 (0.92) |
|
20 |
5 |
64.06 (0.90) |
55.51 (1.10) |
82.00 (0.68) |
67.72 (1.43) |
49.97 (1.57) |
90.46 (0.71) |
| 10 |
71.30 (0.74) |
61.32 (0.99) |
87.49 (0.48) |
71.77 (1.02) |
51.61 (1.24) |
93.51 (0.48) |
| 15 |
75.14 (0.58) |
64.53 (0.81) |
90.98 (0.36) |
72.16 (0.82) |
51.85 (0.97) |
94.97 (0.35) |
| 20 |
77.83 (0.57) |
65.32 (0.81) |
92.69 (0.31) |
73.10 (0.73) |
50.63 (0.89) |
95.12 (0.32) |
The average (standard deviation) of the percent of sites with p ≤ 0.05, in both a simulation with and a simulation without sample heterogeneity is shown, summarized for 1,000 simulations. Tests have been performed under the given significance level α. The per group sample size is n, and the percent CpG sites that are differentially methylated is denoted by R. Results shown are for the scenario in which the case standard deviation was shifted by 1 |
