Patient ID P-value Adjusted P-value S1 0.028 0.505 S2 0.743 1.000 S3 0.019 0.334 S4 0.001 0.019 S5 0.200 1.000 S6 0.757 1.000 S7 0.059 1.000 S8 2.899E-04 0.005 S9 0.003 0.059 S10 0.048 0.866 S11 0.879 1.000 S12 0.090 1.614 S13 8.905E-08 1.603E-06 S14 3.312E-05 0.001 S15 0.013 0.228 S16 4.444E-04 0.008 S17 0.006 0.113 S18 0.020 0.352 S1 = Patient sample 1 P-value = nominal P-value for testing differential expression of patient-specific pathway activities (against mean gene expression of control group) Adjusted P-value = Bonferroni corrected P-value.

Table 2: Significance testing of patient-specific pathway activities for the Oxidative Phosphorylation Pathway.