| Antibiotic Concentration |
Value of K from eqn.(2) calculated using RTM software, with P-value in parentheses |
| Escherichia coli ATCC 25922 |
Pseudomonas aeruginosaATCC 27853 |
Staphylococcus aureusATCC 29213 |
| (mg/l) |
Ampicillin |
Chloram-phenicol |
Gentamicin |
Amikacin |
Ampicillin |
Chloram-
phenicol |
| Control |
0.53876
(0.035) |
0.4479
(0.6735) |
0.04821
(0.819) |
0.13
(0.756) |
0.03685
(0.839) |
0.2772
(0.0648) |
| 0.5 |
0.692
(0.368) |
0.56079
(0.856) |
0.06857
(0.819) |
1.73
(0.43) |
-0.026
(0.878) |
0.4332
(0.849) |
| 1 |
0.59
(0.368) |
0.2664
(0.75) |
0.5607
(0.639) |
0.2525
(0.539) |
-0.4457
(0.1673) |
1.42
(0.707) |
| 2 |
-0.278
(0.75) |
0.0806
(0.794) |
0.15
(0.971) |
0.792
(0.62) |
-0.53
(0.26) |
0.671
(0.96) |
| 4 |
-0.898
(0.2285) |
0.227
(0.628) |
-0.7194
(0.55) |
-0.0013
(1) |
-0.3969
(0.415) |
0.0268
(0.95) |
| 8 |
-1.23
(0.36) |
0.209
(0.941) |
-0.6121
(0.7918) |
-0.7373
(0.995) |
-0.568
(0.191) |
-0.632
(0.944) |
| 16 |
-0.511
(0.66) |
-0.04
(0.945) |
-1.0139
(0.495) |
-0.065
(0.995) |
-0.2478
(0.609) |
-0.1003
(0.94) |
| 32 |
-3.54
(0.064) |
-0.0089
(0.989) |
-0.1791
(0.6486) |
-0.0069
(0.90) |
-0.4627
(0.5916) |
0.05014
(0.967) |
| 64 |
-10.35
(0.083) |
-0.0119
(0.995) |
-0.152
(0.827) |
-0.38
(0.922) |
-0.291
(0.174) |
-0.1814
(0.96) |
| 128 |
-2.35
(0.6083) |
0.024
(0.994) |
-0.5723
(0.1889) |
-0.04121
(0.987) |
-2.25
(0.189) |
-0.02605
(0.982) |
1The values of K obtained by fitting the recorded values of bulk capacitance (Cb) at
different points in time (t) to Equation (2), using the Software R ™ (with P-values,
also calculated by R, in parenthesis) for all samples tested (each with a different
concentration of antibiotic). The boxes corresponding to the MIC value for each
antibiotic-bacteria pair, as determined by criteria described in the text, is marked
with thick borders. The shaded areas indicate the expected MIC range for a given
antibiotic-bacteria pair. |
