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Figure 8: TEM images showing the effect of the γ-Fe2O3/PHFBA nanoparticles on the insulin fibril formation. In the absence (A1, A2) and the presence of: 6% (w/winsulin) of the non-coated γ-Fe2O3 nanoparticles, 9 h after initiation of the fibrillation process (B), or 6% (w/winsulin) of the γ-Fe2O3/PHFBA nanoparticles, 9 h (C) and 50 h (D1 and D2) after the initiation of the fibrillation process. A2 and D2 represents higher magnification of the circled region shown in A1 and D1, respectively. |