| Category |
Name |
ORF No.in BmNPV |
ORF No.in AcMNPV |
Localization |
Function |
Reference |
The phenotype after knock out in BmNPV |
| Replication |
| |
Lef-1 |
6 |
14 |
nucleosome |
DNA primase |
[32] |
C |
| |
DNApol |
53 |
65 |
nucleosome |
DNA polemerase |
[33,34,35,36] |
C |
| |
Helicase |
78 |
95 |
nucleosome |
DNA helicase |
[35,37,38,39,] |
D |
| |
Lef-2 |
135 |
6 |
cell nuclei |
Bind to both DNA and LEF-1; activate late transcription |
[40] |
C |
| Transcription |
| |
P47 |
31 |
40 |
nuclei |
RNA polymerase subunit |
[41,42,] |
D |
| |
Lef-8 |
39 |
50 |
Nuclei |
RNA polymerase subunit |
[43,44] |
D |
| |
Lef-9 |
50 |
62 |
cell nuclei |
RNA polymerase subunit |
[44] |
D |
| |
Lef-4 |
73 |
90 |
cell nuclei |
RNA polymerase subunit |
[41,45,46,47,48] |
D |
| |
Lef-5 |
83 |
99 |
cell nuclei |
initiation factor |
[49] |
D |
| Packaging, assembly, and release |
| |
VP1054 |
43 |
54 |
nucleosome |
structrual protein;
nucleocapsid assembly |
[50] |
C |
| |
Vlf-1 |
63 |
77 |
nucleosome |
lambda integrase; nucleocapsid assembly |
[33,42,51,52,53] |
C |
| |
GP41 |
66 |
80 |
tegument |
ODV protein; BV production |
[54,55] |
B |
| |
ODV -NC42 |
56 |
68 |
capsid |
ODV protein; Assemble nucleocapsid into ODV |
[17,56] |
A |
| |
VP91/P95 |
69 |
83 |
envelope |
Capsid-associated protein |
[57] |
C |
| |
VP39 |
72 |
89 |
capsid |
major capsid protein |
[58,59,60,61] |
C |
| |
P33 |
75 |
92 |
nonstructural |
sulfhydryloxidase; BV/ODV associated protein |
[62,63,64] |
C |
| |
38K |
82 |
98 |
nucleosome |
Nucleocapsid assembly |
[65,66] |
C |
| |
P6.9 |
84 |
100 |
capsid |
DNA binding |
[67,68,69] |
C |
| |
ODV-EC43 |
92 |
109 |
capsid |
BV/ODV Protein |
[70,71,72] |
C |
| |
Alk-exo |
110 |
133 |
nucleosome |
5'-3'exonulcease |
[73,74,75] |
C |
| |
P49 |
118 |
142 |
capsid |
Nucleocapsid assembly |
[76] |
C |
| |
ODV-E18 |
119 |
143 |
envelope |
BV/ODV Protein; BV production |
[77] |
B |
| |
desmoplakin |
54 |
66 |
|
BV production |
[78] |
C |
| Cell cycle arrest and/or interaction with host proteins |
| |
|
67 |
81 |
|
interact with Actin3 in cytoplasm |
[79] |
C |
| |
ODV-EC27 |
120 |
144 |
tegument |
ODV associated protein; cyclin |
[80,81] |
C |
| Oral infectivity |
| |
Pif-2 |
13 |
22 |
envelope |
mediate binding in midgut |
[82,83] |
A |
| |
OEV-E28/19K/Pif4 |
79 |
96 |
envelope |
primary oral infection |
[72,83,84,] |
C |
| |
Pif-3 |
95 |
115 |
envelope |
form a complex with PIF-1 and PIF-2 |
[83,72] |
A |
| |
Pif-1 |
97 |
119 |
envelope |
mediate binding in midgut |
[83,85,86] |
A |
| |
Pif-0/P74 |
115 |
138 |
envelope |
mediate binding in midgut |
[87,88,89,90] |
A |
| |
Pif5/ODV-E56 |
124 |
148 |
envelope |
primary oral infection |
[81,91] |
A |
|
