Table 2

Variables	Timing	G1 Silymarin	G2 N-Acetylcysteine	G3 Selenium	G4 placebo
S. GSH (µg/ml )	Pre	0.593 ± 0.17	0.719 ± 0.24	0.73 ± 0.15	0.57 ± 0.25
S. GSH (µg/ml )	Post	1.604 ± 0.75**	1.48 ± 0.67**	1.47 ± 0.58**	0.56 ± 0.28
S. MDA (µg/ml )	Pre	8.94 ± 0.99	8.26±1.23	8.01 ± 1.1	9.53 ± 2.21
S. MDA (µg/ml )	Post	5.44 ± 1.79**	5.05 ± 1.74**	5.2 ± 1.95**	9.64 ± 2.2
S. IL-8 (pg/ml )	Pre	66.38 ± 40.35	68.53 ± 37.93	58.29 ± 46.9	51.45 ± 35.71
S. IL-8 (pg/ml )	Post	13.2 ± 13.2*	18.93 ± 15.13*	17 ± 11.49*	55.32 ± 41.23

Results represent mean ± Standard deviation **represents highly significant P ≤ 0.01 change between treatment groups and placebo *represents significant P ≤ 0.05 change between treatment groups and placebo

Table 2: Effects of Silymarin, N-Acetylcysteine and Selenium on serum glutathione, malondialdehyde and interleukine-8 for patients with acne compared to placebo after eight weeks.