Parameters Controls (n=45) Mild acne(n=15) Moderate acne(n=15) Severe acne(n=15) Zn(mg/dl) 102.42 ± 18.10 116.67 ± 12.34 NS 95.67 ± 4.58 NS   79.67 ± 7.19 1 Cu(mg/dl) 97.56 ± 14.48 102.67 ± 22.82 NS 98.67 ± 18.85 NS 95.33 ± 15.06 NS Mg(mg/dl) 1.14 ± 0.17 1.29 ± 0.18 NS 1.20 ± 0.18 NS 1.13 ± 0.20 2 BMI: Body Mass Index NS: t-test no significant difference between – mild, - moderate acne types and controls 1t-test significant differences for Zn between each of controls (P=0.0001), mild- (0.0001), and moderate acne (P=0.003) with severe acne type. 2t-test significant difference for Mg between mild acne type and severe acne type (P=0.011)

Table 2: Mean ( ± SD) values of Serum Zinc, Copper, and Magnesium Concentrations in Healthy Male Controls and Patients with Mild-, Moderate,- and Severe Acne Vulgaris.