Figure 2: Blockade of IL-33 attenuates the epidermal thickness in allergic contact dermatitis model mice. (a) An anti-mouse IL-33 antibody or IgG1 isotype control antibody, 10 μg each, was subcutaneously injected into the ears of allergic contact dermatitis model mice on day 9 after sensitization. (b) Ear tissues obtained from the mice on day 15 were subjected to H&E staining (n=8–9/group). Left, IgG1 isotype control antibody-injected mouse; right, anti- IL-33 antibody-injected mouse; arrows, eosinophils. Scale bars, 10 μm.