Figure 2

Figure 2: Naive T cells are present in newborn, infant and adult dermis. Cryosections from neonatal (5 days) and infant (5 months) foreskin and, as positive control, adult male breast skin (19 years) were included and stained with an anti-CD45RA-PE mAb and counterstained with an anti-CD3-FITC mAb. CD3⁺CD45RA⁺ cells (arrows) were found in the dermis of the indicated age groups. Inset shows colocalization of a CD3⁺CD45RA⁺ T cell with a CD3⁺CD4RAT cell. Shown is one representative experiment out of 10. Scale bars: 20 μm. E = Epidermis, D = Dermis.