| Squamous cell carcinoma |
Irregular hyperkeratosis
Epidermal pleomorphism and nuclear enlargement
Architectural disarrangement throughout the epidermis (atypical "honeycomb" pattern)
Round nucleated cells in the granular and spinous layers
Round blood vessels throughout the dermal papilla |
| Basal cell carcinoma |
Orientation of the tumor cells nuclei along the same axis ("polarization")
Tumor silhouettes / Bright tumor islands
Cleft-like dark spaces
Dendritic structures within the tumor islands or in the overlying epidermis
Plump-bright non nucleated cells
Canalicular vessels |
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