ALL Alpha3/Alpha2
High Middle Low
Number of subjects 74 18 38 18
Age, years 69.4 ± 7.6 [52-85] 70.4 ± 6.7 [60-85] 68.4 ± 8.2 [52-83] 70.4 ± 7.4 [57-80]
Sex, female 51 (%) 13 (%) 24 (%) 14 (%)
Education, years 7.6 ± 3.9 [3-18] 6.6 ± 3.6 [4-18] 7.6 ± 3.7 [3-17] 8.3 ± 4.7 [3-18]
Mini mental state exam 27.2 ± 1.7 [23-30] 26.9 ± 1.3 [23-29] 27. ± 1.7 [24-30] 27.4 ± 1.2 [23-30]
Alpha3/alpha2 1.09 ± 0.15 [0.77-1.52] 1.29 ± 0.1*† [1.17-1.52] 1.08 ± 0.0* # [1-1.16] 0.9 ± 0.1# † [0.77-0.98]
Table 1: Demographic and cognitive characteristics in the whole sample, disaggregated for increased levels of Alpha3/ Alpha2 ratio. Numbers denote mean ± standard deviation, number and [range]. p denotes significance on ANOVA (continuous variables) and chi-square test (dichotomous variables).