Figure 2: HFpEF vasculomic network. The pathophysiology of HFpEF is highlighted on the same physiological map shown in Figure 1 with the nodes and edges that represent factors relevant to the etiology of HFpEF highlighted in red to integrate current knowledge about factors related to HFpEF into the overall cardiovascular physiology context. This technique may be useful for initiating the design of vasculomic studies. This figure was created by N. Schaible using freely available software, Cytoscape (cytoscape.org), version 2.8.1. [75].