medication

 Keratoconus patients (n=426)

Matched controls (n=1691)

 Odds Ratio

95% Confidence interval

Ace inhibitors

51(11.97%)

137 (8.04%)

1.6

1.1-2.2

Alpha adrenergic blocking agents

14 (3.29%)

26 (1.53%)

2.2

1.1-4.2

Beta blocking agents

20 (4.69%)

14 (0.82%)

6

3.0-11.9

Biphosphonates

17(3.99%)

32(1.88%)

2.2

1.2-3.9

Nsaids

32 (7.51%)

33 (1.94%)

4.1

2.5-6.7

Corticosteroids

145(34.04%)

146(8.57%)

5.5

4.2-7.2
Leukotriene receptor antagonists

6(1.41%)

4(0.23%)

6

1.7-21.6

Immunosuppressant

5(1.17%)

3(0.18%)

6.7

1.6-28.3
Table 3: Drug associated with renal disease that were significantly used more by keratoconus patients than controls.