Formula Code |
Parameter |
Time (month) |
0 |
1 |
2 |
3 |
F1 |
Appearance
pH
Drug content (%) |
Clear
5.4(0.11)
98.9(0.)22 |
NC
5.07(0.25)
95.9(0.14) |
NC
5.01(0.22)
95.88(0.39) |
NC
5.00(0.11)
95.12(0.99) |
F2 |
Appearance
pH
Drug content (%) |
Clear
5.1(0.55)
99.5(0.6) |
NC
5.45(0.55)
97.23(0.22) |
NC
6.38(0.2)
97.78(0.95) |
NC
6.38(0.19)
96.55(0.99) |
F3 |
Appearance
pH
Drug content (%) |
Clear
5.8(0.33)
97.99(0.39) |
NC
4.94(75)
96.28(0.69) |
NC
4.29(0.22)
97.22(0.99) |
NC
4.3(0.44)
96.88(1) |
F4 |
Appearance
pH
Drug content (%) |
Clear
4.86(0.26)
100.62(0.66) |
NC
4.55(0.6)
98.99(0.25) |
NC
4.55(0.25)
96.55(0.89) |
NC
4.48(0.15)
96.2(1.5) |
F5 |
Appearance
pH
Drug content (%) |
Clear
5.46(0.23)
110.66(0.21) |
NC
5.67(0.1)
101.45(0.44) |
NC
6.2(0.6)
100.669(1) |
NC
6.15(0.23)
99.99(0.95) |
F6 |
Appearance
pH
Drug content (%) |
Clear
5.28(0.65)
109.23(0.22) |
NC
5.37(0.22)
107.13(0.64) |
NC
6.41(0.5)
100.93(0.99) |
NC
6.41(0.22)
100.55(1) |
F7 |
Appearance
pH
Drug content (%) |
Clear
5.99(0.49)
99.98(0.22) |
NC
5.66(0.11)
96.626(0.21) |
NC
5.78(0.25)
96.626(1) |
NC
5.55(0.5)
96.18(0.92) |
F8 |
Appearance
pH
Drug content (%) |
Clear
5.51(0.99)
97.23(0.69) |
NC
4.77(0.66)
96.4(0.22) |
NC
4.22(0.45)
95.22(0.99) |
NC
4.3(0.21)
95.21(1.5) |
F9 |
Appearance
pH
Drug content (%) |
Clear
3.38(0.22)
99.96(0.36) |
Brittle
5.00(0.55)
98.19(0.22) |
Brittle
5.00(0.55)
98.5(0.25) |
Brittle
4.88(0.23)
97.66(0.95) |
F10 |
Appearance
pH
Drug content (%) |
Clear
3.58(0.22)
111.9(0.26) |
Brittle
6.34(0.65)
103.5(0.66) |
Brittle
6.34(0.1)
100.92(1) |
Brittle
6.00(0.1)
99.98(1) |
F11 |
Appearance
pH
Drug content (%) |
Clear
5.65(0.36)
99.7(0.59) |
Brittle
6.53(0.25)
97.972(0.22) |
Brittle
6.58(0.9)
97.19(0.99) |
Brittle
6.2(0.44)
96.99(0.89) |
F12 |
Appearance
pH
Drug content (%) |
Clear
4.6(0.12)
99.99(0.56) |
Sticky
5.06(0.5)
98.04(1) |
Sticky
6.43(0.12)
96.28(0.99) |
Sticky
6.3(0.5)
96.12(0.99) |
F13 |
Appearance
pH
Drug content (%) |
Clear
4.02(0.33)
128.21(0.98) |
Sticky
4.12(0.33)
110.05(1.5) |
Sticky
4.11(0.39)
99.55(1) |
Sticky
4.11(0.66)
99.10(0.96) |
F14 |
Appearance
pH
Drug content (%) |
Clear
4.98(0.22)
109.98(0.96) |
Precipitation
5.33(0.12)
102.45(0.96) |
Precipitation
5.28(0.42)
99.25(1.5) |
Precipitation
5.25(0.12)
98.66(1) |
F15 |
Appearance
pH
Drug content (%) |
Clear
5.89(0.21)
119.99(0.99) |
melt
-
- |
-
-
- |
-
-
- |
F16 |
Appearance
pH
Drug content (%) |
Clear
5.82(0.45)
100.99(0.99) |
melt
-
- |
-
-
- |
-
-
- |
F17 |
Appearance
pH
Drug content (%) |
Clear
5.81(0.23)
99.98(0.89) |
melt
-
- |
-
-
- |
-
-
- |
F18 |
Appearance
pH
Drug content (%) |
Clear
5.3(0.44)
120.96(0.5) |
melt
-
- |
-
-
- |
-
-
- |
F19 |
Appearance
pH
Drug content (%) |
Clear
5.82(0.43)
98.36(0.56) |
melt
-
- |
-
-
- |
-
-
- |
