Treatment Arm Mean Age, y Sex, % Female Male Unknown Brimonidine/timolol (n=1242) 69.8 59.8 39.9 0.2 Dorzolamide/timolol (n=2868) 70.3** 56.3† 43.1 0.6 β-blocker+brimonidine (n=365) 70.0 57.8 41.4 0.8 β-blocker+CAI (n=236) 70.2 52.5* 46.6 0.8 β-blocker+PGA (n=1025) 71.9† 55.9* 44.0 0.1 CAI+brimonidine (n=329) 69.7 56.8 42.6 0.6 CAI+PGA (n=618) 70.3** 57.0 42.6 0.5 PGA+brimonidine (n=1200) 70.3† 56.6* 42.8 0.6 CAI: Carbonic Anhydrase Inhibitor; PGA: Prostaglandin Analogue *p<0.05; **p<0.01; †p<0.0001 vs brimonidine/timolol

Table 1: Baseline demographics of patients with glaucoma included in analyses.