Figure 4: Light microscopy of the trabecular meshwork and Schlemm’s canal (SC) at the first (4a) and second (4b) TLE of Patient 3. Toluidine blue staining. 4c, 4d: Transmission electron microscopy of granuloma (G) at the first TLE. 4e: Transmission electron microscopy of collector channel (CC) at the second TLE. 4a: The Schlemm’s canal (SC) was almost occluded at the first TLE. Most of the trabecular cells disappeared. 4b: The Schlemm’s canal was normally open at the second TLE. 4c: Ultrathin section of the boxed area in 4a. Granuloma (G) composed of epithelioid cells occupying the posterior part of the Schlemm’s canal. 4d: Large magnification of boxed area in 4c. Epithelioid cells had subplasmalemmal linear densities (arrows). 4e: Ultrathin section of the boxed area in 4b. Lymphocytes (L) were observed along the collector channel (CC).