Figure 1: Stressor-dependent gene and protein expression of gp130 in whole retina. A. Gene expression of gp130 in whole retina from young C57, aged C57, young DBA/2 and aged DBA/2 mice, as determined by quantitative PCR. Levels of gene expression are determined by the delta CT method, using GAPDH as the reference gene. Data is represented as percent change in gene expression relative to expression in young C57 retina. Asterisks denote statistical significance (p < 0.05), as compared to expression in young C57 retina. B. Protein concentration of gp130 (pg/ml/μg protein) in membrane fractions of whole retina lysates from young C57, aged C57, young DBA/2 and aged DBA/2 mice, as determined by ELISA. Asterisks denote statistical significance (p < 0.05).