Figure 7: Constitutive expression of gp130 correlates with axonal transport in RGCs and GFAP and glutamine synthetase expression by astrocytes and Muller glia, respectively. Left panels: Regression graphs of fluorescent intensity for gp130 immunolabeling and intensity of cholera toxin-β (CTB) uptake/transport (A), GFAP immunolabeling (B) and glutamine synthetase (GS; C) immunolabeling in the ganglion cell and nerve fiber layers of mid-central to mid-peripheral regions of wholemounted retina from young C57 mice. Data is plotted as intensity of gp130 (y-axis) versus intensity of CTB (A; x-axis), GFAP (B; x-axis) or GS (C; x-axis) in arbitrary units. Solid line indicates regression line based on r2 value. Dashed line indicates the 95% confidence interval. Dotted line indicates predicted values based on r2 and 95% confidence. Right panels: Representative confocal micrographs depicting relationships between gp130 immunolabeling (green) and CTB transport (red; A), GFAP (blue; B), and GS (blue; C) labeling. For all, examples of low (left) and high (right) intensities are provided. Scaling is consistent for all images.