Layer Index |
Healthy |
DM |
MDR |
Across All Macular Regions |
|
|
|
RNFL |
12.38 ± 1.36 |
11.59 ± 1.19 † |
(-13%)10.81 ± 1.38 ‡ |
GCL+IPL |
13.81 ± 2.10 |
(-16%)12.98 ± 1.79 ‡ |
(-21%)10.96 ± 1.87 ‡ |
INL |
4.36 ± 0.84 |
(-15%)4.40 ± 0.78 ‡ |
(-14%)3.74 ± 0.69 ‡ |
OPL |
6.28 ± 1.25 |
(-23%)6.20 ± 1.48 ‡ |
(-24%)4.75 ± 0.74 ‡ |
ONL+IS |
7.59 ± 1.58 |
7.22 ± 1.22 † |
6.52 ± 1.48 † |
OS |
6.09 ± 0.77 |
(-17%)6.42 ± 0.61 ‡ |
(-13%)5.32 ± 0.49 ‡ |
RPE |
6.26 ± 0.52 |
6.61 ± 0.53 † |
6.19 ± 0.43 |
Foveal Region |
|
|
|
RNFL |
7.27 ± 0.93 |
7.03 ± 1.07 † |
(-12%)6.43 ± 1.13 ‡ |
GCL+IPL |
14.93 ± 2.50 |
(-24%)13.98 ± 2.93 ‡ |
(-29%)10.66 ± 2.01 ‡ |
INL |
4.42 ± 0.95 |
(-17%)4.64 ± 1.02 ‡ |
3.87 ± 0.71 † |
OPL |
8.95 ± 2.04 |
(-35%)8.72 ± 3.15 ‡ |
(-36%)5.71 ± 1.40 ‡ |
ONL+IS |
8.55 ± 1.85 |
8.23 ± 1.48 † |
7.28 ± 1.94 † |
OS |
6.37 ± 0.99 |
(-17%)6.62 ± 0.68 ‡ |
(-14%)5.51 ± 0.60 ‡ |
RPE |
6.48 ± 0.63 |
6.85 ± 0.60 |
† 6.48 ± 0.52 |
Parafoveal Region |
|
|
|
RNFL |
9.84 ± 1.05 |
(-11%)9.62 ± 1.00 ‡ |
(-13%)8.57 ± 1.23 ‡ |
GCL+IPL |
16.11 ± 2.53 |
(-17%)15.55 ± 2.12 ‡ |
(-19%)12.97 ± 2.33 ‡ |
INL |
4.75 ± 0.96 |
(-16%)4.82 ± 0.87 ‡ |
(-15%)4.04 ± 0.75 ‡ |
OPL |
5.96 ± 1.26 |
(-17%)6.15 ± 1.25 ‡ |
(-14%)5.11 ± 0.86 ‡ |
ONL+IS |
7.75 ± 1.62 |
7.27 ± 1.19 † |
(-14%)6.66 ± 1.32 ‡ |
OS |
6.02 ± 1.00 |
(-21%)6.52 ± 0.74 ‡ |
(-14%)5.18 ± 0.71 ‡ |
RPE |
5.79 ± 0.64 |
6.32 ± 0.69 † |
5.91 ± 0.68 |
Perifoveal Region |
|
|
|
RNFL |
14.02 ± 1.69 |
(-8%)13.27 ± 1.39 ‡ |
(-13%)12.16 ± 1.68 ‡ |
GCL+IPL |
12.56 ± 1.96 |
11.66 ± 1.61 † |
(-17%)10.46 ± 2.01 ‡ |
INL |
4.19 ± 0.80 |
(-13%)4.15 ± 0.72 ‡ |
(-14%)3.59 ± 0.74 ‡ |
OPL |
4.87 ± 0.94 |
(-14%)4.79 ± 0.79 ‡ |
(-16%)4.11 ± 0.74 ‡ |
ONL+IS |
6.79 ± 1.42 |
6.41 ± 1.12 |
5.92 ± 1.36 † |
OS |
5.88 ± 0.75 |
(-18%)6.28 ± 0.71 ‡ |
(-12%)5.16 ± 0.61 ‡ |
RPE |
6.07 ± 0.55 |
6.34 ± 0.64 † |
5.94 ± 0.54 |
†0.001<p<0.05 and ‡ p<0.001 (ANOVA followed by Newman-Keuls post hoc analysis). For comparisons between MDR and healthy eyes (see MDR column); and between
MDR and DM eyes (see DM column). Changes in percentage are indicated at the upper left of each measure.
SD: Standard Deviation; MDR: Mild Diabetic Retinopathy; DM: Diabetes Mellitus |