Therapeutic purpose - Radiotherapy for skin hemangioma

Wilde et al. 1997 [19]

Hall et al. 1999 [18]

Number of patients

20

E=484; NE=89

Median age at exposure

6 months

< 18 months

Mean age at eye examination

31-46 years

E=46 years; NE=42 years

Eye lens dose

0.02 – 0.12 Gy (non treated side)

0.4 Gy (90% < 1Gy)

Results

13 cases with lens opacities, increase of prevalence with increasing doses

37% of lens opacities E vs. 20% for NE OR/1Gy=1.49 (1.07-2.08) (PSC) OR/1Gy=1.50 (1.15-1.95) (CC)

Diagnostic purpose – Examinations involving X-rays

Klein et al. 1993 [20]

Number of subjects

4926 adults

Mean age at eye examination

43-84 years

Results

Brain scan and PSC: OR=1.45 (1.08-1.95) Brain scan and NC: OR=1.28 (1.02-1.61)

PSC: posterior subcapsular cataract; CC: Cortical cataract; NC: Nuclear cataract; E: exposed; NE: Not exposed
Table 2: Studies on medical exposure.