Genes

Functional annotation

SS2 Strains

Animal models

Origins

Transcription factor (5)
perR PerR, a Fur-like protein Strain SC-19 (China) Balb/c mice (25)
adcR AdcR, a pleiotropic regulator Strain P1/7 (Netherlands) Balb/c mice (1)
ccpA catabolite control protein A Strain 10 (Netherlands) No (23)
argR an ADS-associated repressor of the ArgR/AhrC arginine family Strain 10 (Netherlands) No (9)
rgg Rgg transcription factor 05ZYH33 (China) Piglets (26)
Two component signal transduction system (4)
Ihk-irR A homolog of the Streptococcus pyogenes Ihk/Irr TCS Strain 05ZYH33 (China) CD-1 mice (13)
virR-virS A homolog of the VirR-VirS regulatory system of Clostridium perfringens Strain 05ZYH33 (China) Balb/c Mice (20)
salK-salR Two-component system in the 89K PAI Strain 05ZYH33 (China) Piglets (14)
ciaR-ciaH A two-component system SC19 (China) CD-1 mice & piglets (5)
Orphan response regulator (2)
covR Orphan response regulator (CovR) Strain 05ZYH33 (China) Piglets (16)
revSC21 Orphan response regulator RevSC21 Strain SC21 (China) CD-1 mice  (24)
Table 1: Transcription factors and regulatory systems required for S. suis virulence.