Figure 1: Effect of treadmill exercise with iso-caloric diet on body weight. SENCAR mice at 6 weeks old were divided into ad libitum-fed sedentary control or pair-fed the same amount as the sedentary control. They performed treadmill exercise at 13.4 m/min, 90 min/d, 5 days/week. Body weight was significantly lower in exercised mice, beginning in 2nd week except for 7th week in comparion with the controls. Results are means ± SE, n = 8-12.