Phospholipid group Species* m/z Mol % of total polar lipids†
Control PE PE+IGF-1
PI 36:1 863.6 0.400±0.545a 0.691±0.517b 0.113±0.134a
36:3 859.9 0.039±0.005a 0.005±0.001b UDb
38:4 885.5 6.237±2.036a 4.383±0.681b 5.572±0.430a,b
LysoPC 20:3 546.5 UDa 0.003±0.002a 0.028±0.017b
20:4 544.3 0.258±0.047a,b 0.137±0.012b 0.343±0.110a
20:5 542.3 UDa UDa 0.006±0.004b
22:5 570.4 0.009±0.006a,b UDb 0.023±0.019a
LysoPE 20:4 502.3 0.013±0.006a,b 0.024±0.004a 0.006±0.004b
22:5 528.3 0.007±0.004a,b 0.009±0.005a UDb
ePC 36:1 774.6 0.204±0.053a 0.316±0.036b 0.323±0.048b
ePE 32:1 676.5 UDa 0.005±0.002b UDa
38:1 760.6 0.010±0.006a,b UDb 0.024±0.008a
38:2 758.6 0.357±0.008a 0.496±0.044b 0.481±0.018b
40:3 784.6 UDa 0.008±0.004b UDa
40:4 782.6 0.073±0.005a 0.163±0.020b 0.159±0.006a
ePS 34:1 746.5 0.021±0.010a 0.009±0.005a,b UDb
38:0 804.5 UDa 0.011±0.004b UDa
38:2 800.6 0.026±0.018a 0.071±0.016b 0.061±0.018b
38:3 798.6 0.003±0.002a,b UDb 0.011±0.005a
40:1 830.5 0.011±0.008a,b 0.044±0.014a UDb
40:4 824.6 0.016±0.010a 0.052±0.012b 0.046±0.024a,b
*Total acyl carbons:total double bonds (UD: undetectable values if less than 0.002 mol%);
†Results are means ± SE (n = 5-7 per group). Means with different letters differ significantly, P ≤ 0.05.
Table 1: Effects of restoration IGF-1 on the profile of phospholipids in the mouse skin tissues.