Figure 4: Effect of caspase inhibitor (z-VAD-fmk) on cell death induced by AEL. MCF-7 cells were pre-incubated with 10 μM z-VAD-fmk for 2 h and then treated with various concentrations of AEL. Data values are expressed as mean ± SD of triplicate determinations. Significant differences were compared with the control at *p<0.05, **p<0.01, and ***p<0.001 and by Student’s t-tests.