| 
      MCVdiff= final MCV - initial MCV
        | Estimate | Std. Error | z value | P Value |  
        | (Intercept) 0.76 | 0.21 | 3.66 | <0.001 |  
        | MCVdiff -0.06 | 0.01 | -6.38 | <0.001 |  
        | Gender -0.33 | 0.15 | -2.14 | 0.03 |  
        | Age 0.01 | 0.01 | 2.32 | 0.02 |  The Poisson regression model was evaluated using the number of ED visits as the
      outcome and gender, age and the value obtained by the difference between initial
      MCV and final MCV as independent variables. All covariates in Poisson model
      were statistically significant (p<0.05). The Poisson regression model showed that
      the increase of one unit in the positive difference between initial MCV and final
    MCV resulted in a reduction of approximately 6% in the number of ED visits
 |