Procoagulant factor Main target Application Comercial names Characteristic Referencea Diagnostic tests Ecarin prothrombin Clotting time assay Tirofiban Prothrombin activator Moore [72] Textarin prothrombin Lupus anticoagulant Factor V Leiden Disease   Prothrombin activator Stocker [73] Noscarin prothrombin Factor V Leiden Disease   Prothrombin activator Marsh and Williams [68] RVV-X FX Factor X deficiency Lupus anticoagulant RVV-X Factor X activator Bezeaud et al. [76]; Triplett [77] RVV-V FV Clotting time assay Factor V Leiden Disease RVV-V Factor V activator Schöni [7] Clinical therapy Ancrod Fibrinogen Defibrinogenating agents Viprinex Thrombin-like Bell [64] Batroxobin Fibrinogen Defibrinogenating agents Reptilase; Defibrase Thrombin-like Bell [64]; Qin et al. [81]; Serrano [82] rLopap Prothrombin Bleeding reversor   Prothrombin activator Andrade et al. [9]   Fibrinogen and Factor X Procoagulant for hemorrhage Haemocoagulase Mixture: Thrombin-like and thromboplastin like enzyme McCleary and Kini [69] aThe given references may not be of the first author to describe the respective molecules

Table 2: Exogenous procoagulant factors as diagnostic test reagents and therapeutic drugs.