Hematologic diseases aPTT* b(24’’-36’’)            free PS ** b(F 58-113%) (M 72-123%)      PC** b (70-140%)    AT III** b (70-120%) D-Dimer ( <0.5 μg/ml)
   HSa 28.6 ± 3.1 87.2 ± 15.3 89.4 ± 8.8 93.1 ± 7.8 <0.5
   PK deficita 36.8 ± 4.7 55.6 ± 13.1 64.8 ± 12.1 62.5 ± 5 >0.5
   CD IIa 37.3 ± 5.2 47.4 ± 6 58.7 ± 5.4 59.2 ± 7.8 >0.5
   cITPa 29.7 ± 3.3 91.4 ± 14.3 94.1 ± 7 93.1 ± 7.2 <0.5
   TIa 36.2 ± 2.8 50.7 ± 5.2 58.4 ± 7 60. 2 ± 5 >0.5
    HCa 27.9 ± 2.9  96 ± 11 98 ± 28  103 ± 9 <0.5
a PTT* p< 0.05 PK deficit, CDII, TI vs HS, Citp, HC PS,PC, ATIII** p< 0.05 PK deficit, CDII, TI vs HS, cITP, HC
ªHereditary Spherocytosis: HS; Piruvate Kynase Deficit: PK; Congenital Dyserithropoiesis II: CDII; Chronic Idiopathic Thrombocytopenic Purpura: cITP; β thalassemia intermedia: TI
b Activated Partial Thromboplastin Time: (aPTT), Free Protein C activity: (PC); Protein S: (PS), Antithrombin III: (AT III); D: Dimer
Table 2: Mean values of clotting tests in splenectomized hematologic patients and controls.