Biomarkers |
References |
Cytokines |
Interleukin |
IL-10 |
[32,51] |
|
Immune activation markers |
soluble CD27*1 |
[53] |
|
Chemokine |
CXCL13*1 |
[52] |
DNA |
Tumor-specific DNA methylation |
DAPK, p16, MGMT, p14, p73, etc*2 |
[63] |
RNA |
miRNAs |
miR-17-92 cluster and miR21*1 |
[79] |
*1These biomarkers were tested in the CSF of non-HIV-related PCNSL patients. *2
Tumor-specific methylated DNA in the CSF was not investigated. CSF, cerebrospinal
fluid; IL-10, interleukin-10; miRNAs, microRNAs. |